Margaret Singer was born and raised in Crescent, Oklahoma where she received her earliest musical training and began her career as an accompanist at the age of twelve. After graduating from high school, she continued her studies at Oklahoma College for Women, where she was a student of Jacque Abram, the Artist-in-Residence. She continued her education on with a Fulbright grant to the Royal Music Academy of Music, London.
Upon returning to America, she moved to New York City, where she accompanied in many vocal studios, and eventually served as Assistant Conductor at the New York City Opera. This was followed by engagements with the San Francisco Opera, Opera Company of Philadelphia, and Washington Opera (D.C.).